Glucolisis

It's complicated for you to learn this thing
Main route for metabolism is glucose
I know, I'm with experts and not beginners
And the end product of this pathway is Pyruvate

Glycolysis occurs in all cells
It happens in their cytosol
But hey! Don't break your head, don't lose focus
A bit of medical rap so you don't go crazy
Glucose enters the cell
It has been modified by phosphorylation

And what will it be called?
It will be glucose 6-phosphate, named in this step
And which enzyme is used?
Well, it will depend on the visited cell
We have glucokinase and hexokinase in this

And the latter for all cells except
Beta cells of the pancreas and hepatocytes
In this case, I need glucokinase
And in this reaction, as you hear

One ATP is consumed and ADP is generated
And glucose 6-phosphate
Turns into fructose 6-phosphate
And the enzyme that did this

Is called isomerase, I manifest it to you
That fructose 6-phosphate you'll see
Will become fructose 1,6-bisphosphate
And phosphofructokinase I will make
That by phosphorylation this will be carried out

This consumes another ATP, generates another ADP
And for the exam, I make a rap
And fructose 1,6-bisphosphate
Splits into two, into two triose phosphates
One, into glyceraldehyde 3-phosphate
Two, into dihydroxyacetone phosphate

Reaction catalyzed by aldolase
Glycolysis, a sung lesion, never forgotten
Dihydroxyacetone comes
To continue in the chain, it does what is convenient
It transforms into glyceraldehyde 3-phosphate
Isomerizes to continue in this way

Into glyceraldehyde 3-phosphates, and now we have two
Of glyceraldehyde 3-phosphates, we have two
Glyceraldehyde 3-phosphates, now we have two
Glyceraldehyde 3-phosphates, they are two
Therefore, from here I clarify my people
There are two, equal reactions simultaneously
The glyceraldehydes 3-phosphates were oxidized

And generated NADH
They passed to 1,3-bisphosphoglycerate
And it was by the enzyme they used
Glyceraldehyde 3-phosphate dehydrogenase
Hear it on the bus, learn it at home

1,3-bisphosphoglycerate
Now is 3-phosphoglycerate
And the enzyme is a kinase
An ADP enters and the first ATP is taken out
Phosphoglycerate kinase caused it
When 3-phosphoglycerate was placed

By the mutase enzyme that touched
And took out, the 2-phosphoglycerate that stood out
2-phosphoglycerate dehydrates
Pleasant intervention, by the enolase enzyme
What's up?, this element leaves immediately
And is known as phosphoenolpyruvate

In this last one there is a key enzyme
Pyruvate kinase has the key
And something in the process that I noticed
Every kinase enzyme produces an ATP
And the desired candidate enters
This end product which is pyruvate

And what is the net gain according to the story?
2 ATP, 2 NADH, and 2 Pyruvate
Note: So you can put it in the corner of the mascot
Vakan you will forget if you don't write it down
If pyruvate is oxidized, guess what?
It enters the mitochondria and then to the Krebs Cycle
Instead, anaerobically a tactical process
Pyruvate ferments and turns into Lactic Acid
Don't complicate yourself as I brought you the solution
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